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Projects

Nasal SARS-CoV-2 peptide vaccine

Our protocol for a peptide-conjugate intranasal vaccine, optimized across five revisions for breadth and durability against emerging SARS-CoV-2 variants.

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Modernized variolation

Protocols for collecting mucus samples, inactivating viruses, and administering variolation safely. Additional protocols for decentralized sample collection and sharing.

Vaccine factories in a tube

Protocols for using genetically-modified yeast to generate vaccine factories in a tube. Vaccines can be delivered orally, nasally, or both.

AI for rapid drug repurposing and antiviral combinations design

Leveraging advances in open source data and AI to repurpose existing drugs and GRAS compounds as antivirals. New techniques for combining several weak antivirals into powerful combinations.

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The swiss cheese model for effective biodefense