Even the best vaccines take 7 to 10 days to mount a preliminary adaptive immune response. And full protection often takes additional weeks and boosters to develop. In the event of an outbreak of a serious pathogen, immediate protection is paramount—even if the protection is incomplete or imperfect. Antivirals can be effective immediately but the …

Due to cost, availability, and published efficacy data of another vaccine design, RaDVaC has discontinued its use of its original chitosan and peptide vaccine platform, and has replaced it with the “Prime and Spike” approach published by Mao and colleagues. From the beginning of the SARS-CoV-2 pandemic the Rapid Deployment Vaccine Collaborative (RaDVaC) has designed, …

The Balvi grant will enable continued development, testing, and continuous updates and improvements of open-source vaccine designs and production methods, including “vaccine factory in a tube” technology. Funds will also support build-out of a decentralized scientific network for open sharing of production methods and technologies, as well as clinical trial and immunology data. The Rapid …

Dear Radvackers, As 2021 comes to a close, we see hopeful glimpses of a waning pandemic. Thus far, the omicron variant seems milder, and even though it is spreading rapidly and we are bracing for a surge into 2022, we are also hopeful that we will emerge with much higher immunity from combinations of vaccination …

Version 1.0December 1, 2021 The Omicron variant of SARS-CoV-2 has over 50 mutations, with 32 mutations in the Spike protein alone1. Both of these numbers are far higher than for any previous variant of concern. These mutations are so numerous that they are likely to impact transmissibility and virulence, but in ways that are currently …

The fragility of our global infrastructure has never been more clear. Decades of neglect have rendered public health catastrophically under-equipped to deal with emerging infectious diseases like COVID-19. Despite the scientific progress in scientific tools that enable biomedical development in remarkable time — measurable in hours and days, rather than in months and years — …

COVID-19 has revealed the importance of lowering barriers to vaccine development globally. On May 25, 2021, some of the world’s leaders in science, economics, and policy came together to discuss how open-source vaccinology coan lower costs, increase participation, catalyze innovation, and improve access to future vaccines. The Rapid Vaccine Deployment Collaborative (RaDVaC) began in March …